Clinical Trials

A great way to help others and yourself!

Pentucket Medical Associates, in our continuing efforts to improve and offer advanced treatments, are involved in several clinical trials and are currently enrolling participants.

NOTE: This is a list of currently active trials. For a list of completed trials / research, please visit our Research page.

Clinical trials are entirely voluntary and patients may withdraw at anytime, for any reason. We are currently participating in the following studies (please click on the title of any one to learn more):

AIM HIGH: Niacin Plus Statin to Prevent Vascular Events
The purpose of this study is to determine whether raising “good cholesterol” with a drug based on the vitamin niacin, while lowering “bad cholesterol” with a statin drug, can prevent more heart disease than the statin alone.

ALTITUDE
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Determine Whether, in Patient with Type 2 Diabetes at High Risk for Cardiovascular and Renal Events, Aliskiren, on Top of Conventional Treatment, Reduces Cardiovascular and Renal Morbidity and Mortality.

ARISTOTLE
A Phase III, Active (Warfarin) Controlled, Randomized, Double-Blind, Parallel Arm Study to Evaluate Efficacy and Safety of Apixaban in Preventing Stroke and Systemic Embolism in Subjects With Nonvalvular Atrial Fibrillation

IMPROVE IT
Study to Establish the Clinical Benefit/Safety of Vytorin (Esetimibe/Simvastatin Tablet) vs Simvastatin in Subjects with Acute Coronary Syndrome (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial-IMPROVE IT)

RE-LY
Randomized Evaluation of Long Term Anticoagulant Therapy (RE-LY) Comparing the Efficacy and Safety of Two Blinded Doses of Dabigatran Etexilate With Open Label Warfarin For the Prevention of Stroke and Systemic Embolism in Patients With Non-Valvular Atrial Fibrillation: Prospective, Multi-Centre, Parallel-Group, Non-Inferiority Trial.

TOPCAT
Trial of Aldosterone Antagonist Therapy in Adults with Preserved Ejection Fraction Congestive Heart Failure (TOPCAT).